The Unit of Preventive Gynecology encompasses the fields of prevention, surveillance and diagnosis of gynecologic cancerousand pre-cancerous lesions. The clinical activities involve 16 gynecologists. The results of the research activities are published in peer reviewed journals, IF was 62,755 in 2013, with 22 publications. The Unit has a high experience in laser surgery for cervical, vaginal, and vulvar pre-cancerous and cancerous lesions with approximately 750 laser treatments on lower female genital tract diseases yearly. HPV test and HPV genotyping are used for the management, diagnosis and follow-up of cervical precancers and cancers. P16 and other biomarkers are used in screening and triage of borderline lesions; 2.000 colposcopic exams are performed yearly.
Primary prevention of HPV related pre-cancerous and cancerous lesions is the goal of our HPV vaccination centre, were both adolescents and women in older ages can receive HPV vaccination. The Unit is involved in the early detection of ovarian cancer as in general population as in high risk of patients with BRCA1/2 mutation or history of previous breast cancer: during 2013 more than 6.000 transvaginal or transabdominal pelvic US have been performed and about one hundred prophylactic salpingo-ophorectomies.
Our team is also dedicated to the diagnosis, management, and follow-up of endometrial abnormalities and early endometrial cancer through transvaginal US and hysteroscopy. More than 350 diagnostic and operative hysteroscopies are performed yearly for uterine polyps and abnormal uterine bleeding. Conservative treatment includes hormonal therapy of endometrial atypical hyperplasia and early endometrial cancer with progestational agents.